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Vanda loses constitutional fight over FDA's drug talks with competitors

The FDA dodged claims from Vanda Pharmaceuticals that it allegedly violated the US Constitution by recommending the same drug specifications for both Vanda and its generic competitors. The opinion,...

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AstraZeneca exec stresses Calquence's patent life ahead of next Medicare...

AstraZeneca says it plans to participate in the next round of Medicare negotiations under the Inflation Reduction Act. But this time around, the company says it’s dealing with a whole different set of...

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Teva’s MS drug and generics to add black box warning for anaphylaxis

The FDA has issued a new boxed warning for Teva Pharmaceuticals' multiple sclerosis drug Copaxone and generic versions marketed by other companies after some patients had serious allergic reactions....

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Anthos' detailed mid-stage data back its anticoagulant, but can the drug...

Anthos Therapeutics’ anticoagulant poses a lower risk of bleeding events than Bayer and J&J’s Xarelto when used to prevent blood clots in atrial fibrillation patients, full results from a mid-stage...

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BioMarin's James Sabry talks biotech M&A, dealmaking in 2025

SAN FRANCISCO — Not many biotechs survive beyond 25 years, let alone get multiple drugs approved and turn a profit. BioMarin Pharmaceutical has done all that, but finds itself navigating an unusual...

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Health Tech startup Innovaccer lays out its acquisition strategy

Innovaccer is buying up health tech companies with the goal of providing healthcare organizations with a simple place to go for a number of tools. The Silicon Valley-based startup sells tools to...

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FDA delays decision on Stealth’s Barth syndrome drug; TargetRx raises $50M

Plus, news about Valneva and Ab&B Bio-Tech: FDA delays decision on Stealth BioTherapeutics drug to April 29: The company’s elamipretide is being developed for Barth syndrome, a rare genetic...

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AbbVie partners with Neomorph in latest molecular glue deal

Neomorph is back at it again with another pharma collaboration. The startup, which is backed by Deerfield Management and the Dana-Farber Cancer Institute, secured another partnership for its molecular...

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What health tech wants from a Trump administration

We’re in the first week of the second Trump administration, and it’s becoming clearer how it might impact healthcare technology. Notably, President Donald Trump revoked the Biden Administration’s AI

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Catalent to make CAR-T for Galapagos; Kindeva gets $129M for nerve agent...

Welcome to Endpoints News’ manufacturing briefs, where we bring you essential news on new builds, collaborations, recalls and more. Catalent said it will manufacture Galapagos’ clinical-stage CAR T...

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Purdue, Sacklers reach new $7.4B opioid settlement after SCOTUS rejection

Purdue Pharma and the Sackler family have agreed to a $7.4 billion settlement in a longstanding legal battle over the nation’s opioid epidemic. The deal, announced Thursday, comes months after the...

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Teva, Astellas plan to participate in IRA drug price negotiations

At least three drugmakers say they will participate in the next round of Medicare negotiations under the Inflation Reduction Act, even though they continue to criticize the process as “price setting.”...

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As another Trump term gets underway, pharma advisors get comfortable with...

What will President Donald Trump's team do on healthcare? Nobody knows for sure. That was the general agreement among the policy experts who advise the drug industry last week at the JP Morgan...

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UnitedHealth Group names Tim Noel as next insurance CEO

UnitedHealth Group has named a new CEO to lead its health insurance business, following the murder of the division’s former top executive in December. The role will be filled by Tim Noel, a company...

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Obesity biotech Aardvark files for IPO to advance oral drug

Aardvark Therapeutics filed for an IPO Thursday night, making it the sixth biotech in line this year for a potential listing on the Nasdaq. The San Diego biotech is trying to ...

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ALX Oncology to make case for accelerated approval with evorpacept in gastric...

ALX Oncology is forging ahead with a treatment approach that has long been abandoned by other drugmakers, eyeing a potential accelerated approval pathway for its CD47-targeting drug in gastric cancer...

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Moderna information chief to retire next month; Pharming looks to Flagship...

Moderna’s chief information officer Brad Miller is “retiring” in February, a company spokesperson confirmed to Endpoints News. His roughly two-year stint followed more than five years in top executive...

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Novo Nordisk’s amycretin prompts 22% weight loss in early obesity trial

Novo Nordisk’s subcutaneous form of amycretin achieved estimated weight loss of 22% at six months in a Phase 1b/2a clinical trial, the Danish company said Friday. The data are highly competitive ...

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AstraZeneca allocates $570M for Canadian expansion, looks to add 700 new jobs

AstraZeneca is looking to increase its presence north of the US border. The UK pharma said it is budgeting $570 million to expand its footprint in Canada, which will help create more than 700 new ...

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Boehringer merges cancer vaccine and oncolytic virus teams; Dantari sells off...

Plus, news about Madrona and Abdera: Boehringer Ingelheim combines two cancer units: The drugmaker is merging its cancer vaccine unit AMAL Therapeutics and its oncolytic virus team ViraTherapeutics,...

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