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China's drug development explosion forces a US biotech reckoning

In 2019, Stanford University professor Irv Weissman and a colleague published a paper that represented a new way to target some aggressive cancers. Shortly after, they did what many researchers do when...

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What to make of UnitedHealth Group’s rebate move

In its first earnings since the murder of UnitedHealthcare CEO Brian Thompson, UnitedHealth Group made a move that caught industry insiders’ attention. The healthcare giant said its pharmacy benefit...

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Sanofi says no supply interruptions after landing FDA warning letter for US site

A new FDA warning letter for French pharmaceutical company Sanofi cited a handful of issues at its biologics factory in Massachusetts. The letter, published on Tuesday, was handed to Sanofi on ...

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J&J's Spravato wins expanded label for depression as singular treatment

Johnson & Johnson’s Spravato nasal spray received a label expansion on Tuesday, now approved as a standalone treatment for major depressive disorder in adults after two oral antidepressants fail,...

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Renewed mifepristone fight will test Trump’s abortion stance

A revived legal challenge to the abortion pill mifepristone will be an early test for President Donald Trump’s administration and his appetite for further weighing in on reproductive health access in...

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US withdrawal from WHO could jeopardize information sharing

The Trump administration’s decision to withdraw from the World Health Organization could complicate US access to health information that’s vital for pharmaceutical companies, academics said Tuesday....

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Oncology biotech ArriVent does another China ADC deal, this time with Lepu...

Bing Yao's ArriVent BioPharma has inked another licensing deal with a Chinese biopharma. The late-stage oncology biotech is picking up a new antibody-drug conjugate from Shanghai-based Lepu Biopharma,...

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GLP-1s can cut the risk of Alzheimer’s. What does that mean for Novo Nordisk?

A new study found that patients taking GLP-1s to treat type 2 diabetes have a lower risk of developing Alzheimer’s disease, potentially opening the door to another lucrative category for Novo Nordisk....

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Regeneron CSO George Yancopoulos on AI's hype and potential

SAN FRANCISCO — Just over 20 years ago, the people of California voted to spend billions of dollars on an exciting new idea to remake medicine. Agreeing to put $3 billion toward ...

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Inhibrx’s early colorectal cancer data clouded by patient death

One of Inhibrx Biosciences’ antibody candidates has shown encouraging early efficacy in colorectal cancer. But its safety is under scrutiny after a patient enrolled in the Phase 1 trial died. The...

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J&J’s Spravato hit $1B in revenue in 2024

Johnson & Johnson’s burgeoning depression treatment Spravato eclipsed $1 billion in revenue in 2024 as the pharma’s neuroscience pipeline comes into view. In its fourth-quarter earnings on...

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Tris Pharma declares Phase 3 win for 'opioid-like' painkiller. Can it sell?

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Shanghai Bao, Sichuan Biokin file IPOs in Hong Kong; Disc's $200M offering

Plus, news about Rivus and Crown Labs: Two Chinese biotechs file for stock listings in Hong Kong: Shanghai Bao Pharmaceuticals and Sichuan Biokin Pharmaceutical join a queue of Chinese drug developers...

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Xilio reports handful of responses for combo in colorectal cancer

Xilio Therapeutics said its anti-CTLA-4 produced promising initial data in certain colorectal cancer patients enrolled in a mid-stage trial. But the drug’s future is uncertain as the company grapples...

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RFK Jr. says he’ll divest interests in CRISPR Therapeutics if confirmed for...

HHS Secretary nominee Robert F. Kennedy Jr. will divest his interests in several biopharma companies, including CRISPR Therapeutics and Dragonfly Therapeutics, if confirmed by the Senate, he said in a...

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Updated: Biogen enacts layoffs across its research unit

Biogen is laying off staff across its research unit, marking one of the most concerted strategic decisions from Jane Grogan since she took over the department. A company spokesperson said in a...

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Health navigation company Quantum Health lays off 4% of workforce

Longtime digital health company Quantum Health has laid off workers days after it appointed a new CEO, Endpoints News has learned. Founded in 1999, private equity-backed Quantum provides services for...

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Samsung Biologics hits revenue high, secures largest contract to date

Samsung Biologics closed 2024 on several high notes, reaching its highest annual revenue to date — and just a week ago, securing its largest client contract so far. Samsung Bio pulled in a record-high...

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Chinese startup begins first clinical trial using CRISPR to edit cells...

A little-known Chinese biotech startup has zipped ahead of US companies in one of the gene editing field’s most competitive races. YolTech Therapeutics announced Monday that it started a clinical trial...

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J&J reinforces Caplyta blockbuster projections, won't shelve neuro prospects

Johnson & Johnson made the largest splash at this year’s JP Morgan Healthcare Conference, acquiring Intra-Cellular Therapies and its neuropsychiatric drug Caplyta for $14.6 billion. On the...

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