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Neumora's major depression drug flunks first of three Phase 3 trials

Neuroscience drug developer Neumora Therapeutics released highly anticipated results from the first of three Phase 3 trials for its experimental major depression drug, saying Thursday that navacaprant...

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The top biotech megarounds of 2024

2024 was the year of the private megaround. Nine-figure financings dominated biotech's venture funding landscape, with 96 such rounds tallied by Endpoints News. The bevy of megarounds drowned out...

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Hutchmed’s divestiture; Xgene reports Phase 2b win for non-opioid pain drug

Plus, news about Hookipa and Capricor Therapeutics: Hutchmed divests 45% stake in Chinese company: Hutchmed will get about $608 million in cash by divesting Shanghai Hutchison Pharmaceuticals Limited,...

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Regeneron buys London-based ocular biotech

Regeneron, maker of the blockbuster ophthalmology medicine Eylea, has acquired an ocular biotech, the large biopharma confirmed to Endpoints News on Thursday. The London-area biotech, named Oxular, was...

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FDA adcomm to review Novartis' Fabhalta in ultra-rare kidney disease

The FDA's Cardiovascular and Renal Drugs Advisory Committee is set to meet Feb. 24 to discuss Novartis' latest submission of Fabhalta in an ultra-rare kidney disease in which about half of patients...

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Pennsylvania Blue Cross insurer restricts coverage of medicines granted FDA...

A Blue Cross Blue Shield licensee serving parts of Pennsylvania says it will not cover some therapies granted accelerated approval for at least 18 months after the FDA signs off. The

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Biopharma to raise more than 1,000 drug prices in 2025, advisory firm predicts

Drugmakers are expected to increase list prices on more than 1,000 medicines this year, and already raised the prices on about 250 drugs on Jan. 1, according to an analysis by the consultancy firm 3 ...

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After CagriSema, eyes are on Lilly’s oral GLP-1 as next key obesity play

With the disappointment of Novo Nordisk’s injected CagriSema in obesity at the end of 2024, there are questions around how much more injected next-gen weight loss ...

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GSK’s Nucala bags another China approval, but biggest test yet to come

GSK’s blockbuster respiratory drug Nucala has secured a China label expansion for certain patients with inflamed sinuses. But a more important challenge on the way to hitting its multibillion-dollar...

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Novo petitions FDA over Victoza compounding as first generic wins approval

Novo Nordisk is continuing its citizen petition crusade at the FDA, this time aiming to stop the compounding of Victoza, its blockbuster GLP-1. The push comes as the regulator late last month

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Eli Lilly seeks to join lawsuit over end of tirzepatide shortage

Eli Lilly has asked to intervene in litigation between a compounding pharmacy trade group and the FDA over the agency’s decision to remove Lilly’s blockbuster obesity and diabetes drug tirzepatide from...

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Florida car dealer joins insulin pricing fight against Eli Lilly, Sanofi

A Florida-based car dealer has joined mounting litigation against Eli Lilly, Novo Nordisk and Sanofi over what it calls the “exorbitant” price of insulin. Braman Motors is the first private company to...

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Neumora fails Ph3 depression study; Our review of 2024 megarounds; Pfizer...

Welcome back to Endpoints Weekly, your review of the week’s top biopharma headlines. Want this in your inbox every Saturday morning? Current Endpoints readers can visit their reader profile to add...

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